Without much details, I just verify what you reported, that was the UV editor been shown in the wrong display - which I could verify.
Please, also define your monitor's layout, then I can test with the same settings.
1-2 / 2-1 - left/right/up/down
Please, also define your monitor's layout, then I can test with the same settings.
1-2 / 2-1 - left/right/up/down